Nature Communications (Aug 2020)

Enhancing myocardial repair with CardioClusters

  • Megan M. Monsanto,
  • Bingyan J. Wang,
  • Zach R. Ehrenberg,
  • Oscar Echeagaray,
  • Kevin S. White,
  • Roberto Alvarez,
  • Kristina Fisher,
  • Sharon Sengphanith,
  • Alvin Muliono,
  • Natalie A. Gude,
  • Mark A. Sussman

DOI
https://doi.org/10.1038/s41467-020-17742-z
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 20

Abstract

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Despite recent progress to advance cardiac cell-based therapy for patients, heart failure mortality rivals most cancers. Here, the authors describe an approach to control and pattern 3 distinct human cardiac cell populations to promote superior repair and regeneration after myocardial infarction.