Drug and Psychedelic drug are a problem causing mental conflicts in families and communities, and everyone strives to keep teenagers and young people away from it. The purpose of this study was to determine the prevalence and associate factors in the use of ecstasy in young people aged 19-29 years in Iran. By recognizing effective factors, we may reduce the consumption of this drug. This study was conducted in 13 provinces of Iran, in 2013. Through multi-stage sampling, 3246 young people aged 19 to 29 years old entered the study. Weighted Multivariate logistic regression was used to measure the relationship between ecstasy consumption and other variables. The prevalence of ecstasy use in this study was 5.3% (with a 95% confidence interval of 3.7and 6.9). Based on the findings of the Multivariate Analysis, Sex(AOR): 2.61 (95% CI 1.14.4.08), Know a person among family members, relative or friends who use methamphetamine: (AOR): 0.56 (95% CI: 0.33.0.97 Know a person among family members, relative or friends who use ecstasy: (AOR): 6.04 (95% CI: 3.10, 11.77) and history of extramarital sex: ( AOR): 3.23 (95% CI: 2.09.4.99) and having knowledge of Psychedelic drug use (AOR): 1.90 (95% CI: 184.108.40.206) had significant relationships with ecstasy consumption. Extending training programs to make people knowledge of the complications of taking this drug will reduce the demand and inclination of people, especially the youth, towards it. It also seems that the reduction of sexual relations outside marriage and the reduction of relationship with those who use ecstasy may be associated with a reduction in ecstasy use. Men also need more care than women.