PLoS ONE (Jan 2021)

Non-Invasive radial pressure wave analysis may digitally predict women's risks of type 2 diabetes (T2DM): A case and control group study.

  • Chih-Yu Chen,
  • Kuo-Meng Liao,
  • Sheng-Hung Wang,
  • Su-Chiu Chen,
  • Chen-Jung Chang,
  • Tien-Chung Wang,
  • Gin-Chung Wang

DOI
https://doi.org/10.1371/journal.pone.0259269
Journal volume & issue
Vol. 16, no. 10
p. e0259269

Abstract

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BackgroundWomen not only have worse diabetes complications, but also have menstrual cycle, pregnancy, and menopause which can make managing diabetes more difficult. The aim of this study was to investigate if radial pressure wave analysis may non-invasively screen for women's risk of type 2 diabetes.MethodsSpectrum analysis of the radial pressure wave was performed to evaluate the first five harmonic components, C1 to C5. The study consisted of a total of 808 non-pregnant female subjects aged 20-95 over the period of 4 years, and 404 of them were diagnosed with Type 2 diabetes as the case group.ResultThe first five harmonic components are significantly different in a comparison of the case group and the control group. In the logistic regression analysis, T2DM was found to be associated with C1 (OR = 1.055, CI = 1.037-1.074, p ConclusionWe thus concluded that pulse spectrum was a non-invasive predictor for women's risk of T2DM.