Communications Biology (Jul 2021)

DeepEMhancer: a deep learning solution for cryo-EM volume post-processing

  • Ruben Sanchez-Garcia,
  • Josue Gomez-Blanco,
  • Ana Cuervo,
  • Jose Maria Carazo,
  • Carlos Oscar S. Sorzano,
  • Javier Vargas

DOI
https://doi.org/10.1038/s42003-021-02399-1
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 8

Abstract

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Sanchez-Garcia et al. present DeepEMhancer, a deep learning-based method that can automatically perform post-processing of raw cryo-electron microscopy density maps. The authors report that DeepEMhancer globally improves local quality of density maps, and may represent a useful tool for novel structures where PDB models are not readily available.