mBio (Feb 2021)

Antibody Landscape Analysis following Influenza Vaccination and Natural Infection in Humans with a High-Throughput Multiplex Influenza Antibody Detection Assay

  • Zhu-Nan Li,
  • Feng Liu,
  • F. Liaini Gross,
  • Lindsay Kim,
  • Jill Ferdinands,
  • Paul Carney,
  • Jessie Chang,
  • James Stevens,
  • Terrence Tumpey,
  • Min Z. Levine

DOI
https://doi.org/10.1128/mBio.02808-20
Journal volume & issue
Vol. 12, no. 1

Abstract

Read online

Repeated influenza vaccination and natural infections generate complex immune profiles in humans that require antibody landscape analysis to assess immunity and evaluate vaccines. However, antibody landscape analyses are difficult to perform using traditional assays.