Brain Targeting of Acyl-CoA:Cholesterol O‑Acyltransferase‑1 Inhibitor K‑604 via the Intranasal Route Using a Hydroxycarboxylic Acid Solution

• Kimiyuki Shibuya,
• Shigeru Morikawa,
• Masayoshi Miyamoto,
• Shin-ichiro Ogawa,
• Yoshihiko Tsunenari,
• Yasuomi Urano,
• Noriko Noguchi

Affiliations

Kimiyuki Shibuya

Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., Ltd., Higashimurayama, Tokyo, Japan

Shigeru Morikawa

Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., Ltd., Higashimurayama, Tokyo, Japan

Masayoshi Miyamoto

Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., Ltd., Higashimurayama, Tokyo, Japan

Shin-ichiro Ogawa

Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., Ltd., Higashimurayama, Tokyo, Japan

Yoshihiko Tsunenari

Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., Ltd., Higashimurayama, Tokyo, Japan

Yasuomi Urano

Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Kyoto, Japan

Noriko Noguchi

Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Kyoto, Japan