Journal of Rare Diseases (Oct 2024)

Lemierre syndrome due to Klebsiella pneumoniae: a rare case report with review of literature

  • N. Mohan Rangan,
  • Anup Kumar Singh,
  • Rekha C. Yadav,
  • Indranil Deb Roy,
  • Kapil Tomar,
  • Neha Singh,
  • Vasanthanarayanan R

DOI
https://doi.org/10.1007/s44162-024-00054-x
Journal volume & issue
Vol. 3, no. 1
pp. 1 – 10

Abstract

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Abstract Lemierre’s syndrome, a forgotten clinical entity, is characterised by septic thrombophlebitis of the internal jugular vein due to oropharyngeal infection. In the past, it was mainly associated with Fusobacterium necrophorum infections. We present a unique case report of Lemierre’s syndrome due to Klebsiella pneumoniae. Patient reported with progressive swelling involving right side of the neck that eventually increased in size. After confirming the diagnosis through CECT, patient was managed through combined medical and surgical therapy in the form of incision and drainage, targeted antibiotic therapy, glycaemic control and anticoagulation therapy. This case report highlights the association of poor glycaemic control in the pathogenesis and the isolation of Klebsiella pneumoniae as the rare organism of Lemierre’s syndrome.

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