RUDN Journal of Medicine (Dec 2011)

Early pregnancy and pandemic flu А(Н1N1)09

  • T E Belokrinitskaya,
  • A O Zolotuhina,
  • E A Koshmeleva,
  • A Yu Trubitcina,
  • E A Fesik

Journal volume & issue
Vol. 0, no. S5
pp. 103 – 110

Abstract

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We studied the course of pregnancy at 159 patients with flu A(H1N1)09 on early pregnancy terms. Control group consisted of 100 pregnants without flu which were in I-st trimester of gestation in the center of a pandemic flu during the same time. Reproductive losses in I trimester of pregnancy complicated by flu A(H1N1)09 were 32,1% (in a control group – 0%). Fetus malformations and spontaneous abortions are more often arose at a flu on 5–8 th weeks of gestation. There is a dependence between the mother's fever and early losses of pregnancy. There is not interrelation between a hyperthermia at the pregnant and fetus malformations. Oligohydramnion, II-nd stage of fetal hypotrophy and preterm labor are more often developed subsequently at patients with a flu A(H1N1)09 in I trimester of pregnancy. Preventive maintenance and flu treatment by an antiviral drags of Arbidolum in early terms of pregnancy reduces frequency of spontaneous abortions and doesn't render teratogenic influence.

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