A case report of ABO-incompatible kidney transplant in human immunodeficiency virus-positive patient coinfected with both hepatitis B and hepatitis C viruses: A case report

Abstract

Individuals with human immunodeficiency virus (HIV) are at increased risk for end-stage kidney disease (ESKD). Kidney transplantation is the best treatment for HIV-positive ESKD patients. There are many challenges such as interactions between antiretroviral drugs and immunosuppressants, coinfection with hepatitis B (HBV) or/and C (HCV) viruses, and a higher risk of posttransplant infections and malignancies. We should not defer HIV-positive kidney transplants perceiving these medical complexities, instead employ a multidisciplinary approach to achieve successful transplantation. For HIV-positive ESKD patients, ABO-incompatible (ABOi) kidney transplantation and considering HIV-positive kidney donors are successful strategies for increasing the donor pool. We report a case of an HIV-positive ESKD patient who had coinfection with both HBV and HCV viruses and successfully underwent an ABOi live-related kidney transplant.

Keywords

• abo-incompatible kidney transplant
• double filtration plasmapheresis
• hepatitis b virus
• hepatitis c virus
• human immunodeficiency virus-positive
• posttransplant infections