Chemo-enzymatic cascades to produce cycloalkenes from bio-based resources

Shuke Wu; Yi Zhou; Daniel Gerngross; Markus Jeschek; Thomas R. Ward

doi:10.1038/s41467-019-13071-y

Nature Communications (Nov 2019)

Chemo-enzymatic cascades to produce cycloalkenes from bio-based resources

Shuke Wu,
Yi Zhou,
Daniel Gerngross,
Markus Jeschek,
Thomas R. Ward

Affiliations

Shuke Wu: Department of Chemistry, University of Basel
Yi Zhou: Department of Chemistry, University of Basel
Daniel Gerngross: Department of Biosystems Science and Engineering, ETH Zurich
Markus Jeschek: Department of Biosystems Science and Engineering, ETH Zurich
Thomas R. Ward: Department of Chemistry, University of Basel

DOI: https://doi.org/10.1038/s41467-019-13071-y
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 10

Abstract

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Cycloalkenes are bulk petrochemicals that are currently obtained from fossil fuels. Here, the authors developed multi enzyme pathways in combination with a Ru-catalyzed metathesis reaction for the one-pot production of cyclopentene, cyclohexene, and cycloheptene from olive oil-derived intermediates.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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