Synthesis and Preliminary Antibacterial Study of New 2-Mercapto-1, 3- Benzothiazole DerivativesWith Expected Biological Activity

Abstract

Benzothiazoles are bicyclic ring system which have multiple applications. as antitumor , antiviral , antibacterial , anthelmintic and some of them showed glucose level.20 lowering effect. Accordingly, research is conducted to synthesize and evaluate some new derivatives as antibacterial agents by linking 2-aminobenzothiazoles with glycine and glycine derivatives. S-benzo[d]thiazol-2-yl2-(2-(2,4-dinitrophenyl)hydrazinyl) ethanethioate has been tested on hospital strains of E.coli and pseudomonas and found to have good activity at different concentrations.

Keywords

• benzothiazoles , antibacterial , chloroacetyl chloride