Diabetes, Metabolic Syndrome and Obesity (Feb 2022)

The Association of the Prevalence of Depression in Type 2 Diabetes Mellitus with Visual-Related Quality of Life and Social Support

  • Ding X,
  • Rong S,
  • Wang Y,
  • Li D,
  • Wen L,
  • Zou B,
  • Zang D,
  • Feng K,
  • Liang Y,
  • Wang F,
  • Zhai G

Journal volume & issue
Vol. Volume 15
pp. 535 – 544

Abstract

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Xiaoxia Ding,1 Shisong Rong,2 Yu Wang,1 Dong Li,1 Liang Wen,1 Bo Zou,1 Dongxiao Zang,1 Kemi Feng,3 Yuanbo Liang,3 Fenghua Wang,4 Gang Zhai1 1Department of Ophthalmology, Fushun Eye Hospital, Fushun, Liaoning, People’s Republic of China; 2Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear, Boston, MA, USA; 3Department of Ophthalmology, the Affiliated Eye Hospital, School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 4Department of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Laboratory, Beijing, People’s Republic of ChinaCorrespondence: Gang Zhai, Fushun Eye Hospital, No. 1 Hupo Street, Xinfu District, Fushun, Liaoning, 113008, People’s Republic of China, Email [email protected]: To report the prevalence of depression and its association with vision-related quality of life and social support in a type 2 diabetes mellitus (T2DM) population.Methods: Patients were recruited from a community-based study, Fushun Diabetic Retinopathy Cohort Study (FS-DIRECT), conducted between July 2012 and May 2013 in China. Depression was assessed using the Centre for Epidemiological Studies Depression Scale (CES-D). Vision-related quality of life was evaluated using the Visual Function Questionnaire-25 (VFQ-25). Social support was captured with the Social Support Rating Scale (SSRS). Generalized linear models were used to estimate the individual and joint association of VFQ-25 composite score (VFQCS) and SSRS score (SSRSS) with depression.Results: A total of 1618 subjects (60.9% female) aged 61.69 ± 8.72 years in an urban district of Jiangjun Street, Fushun City, Liaoning province, Northeast China from July 2012 to May 2013 were recruited, of which, 23.36% (95% CI: 21.30– 25.42%) were identified with depression. Every 14.1 increase in VFQ-25 composite score decreased the risk of depression by half (OR = 0.5; 95% CI: 0.4– 0.6); with the elevation of 10.0 SSRS score the risk of depression decreased by 40% (OR = 0.6; 95% CI: 0.5– 0.7). Patients with the VFQCS less than 91.3 and SSRSS less than 38.0 had 5.9 times more risk of depression (OR = 5.9; 95% CI: 3.6– 9.7). Age (over 60 years) (OR = 0.6; 95% CI: 0.4– 0.9) and medical history of cardiovascular disease (OR = 1.7; 95% CI: 1.1– 2.5) were independently correlated with depression symptom.Conclusion: The prevalence of depression is high among patients with T2DM in urban district in northeast China. Vision-related quality of life and social support scores are significantly associated with depression. Measures should be taken to screen depressive symptoms in patients with type 2 diabetes patients. These patients need to be intervened with appropriate and effective treatment as early as possible. Meanwhile, behavioral health specialists should guide the patient to get and use social support sources effectively.Keywords: diabetic retinopathy, depression, quality of vision, Visual Function Questionnaire-25, Social Support Rating Scale

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