JACS Au
(Aug 2024)
Conformational Modulation of a Mobile Loop Controls Catalysis in the (βα)8‑Barrel Enzyme of Histidine Biosynthesis HisF
- Enrico Hupfeld,
- Sandra Schlee,
- Jan Philip Wurm,
- Chitra Rajendran,
- Dariia Yehorova,
- Eva Vos,
- Dinesh Ravindra Raju,
- Shina Caroline Lynn Kamerlin,
- Remco Sprangers,
- Reinhard Sterner
Affiliations
- Enrico Hupfeld
- Institute of Biophysics and Physical Biochemistry, Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Germany
- Sandra Schlee
- Institute of Biophysics and Physical Biochemistry, Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Germany
- Jan Philip Wurm
- Institute of Biophysics and Physical Biochemistry, Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Germany
- Chitra Rajendran
- Institute of Biophysics and Physical Biochemistry, Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Germany
- Dariia Yehorova
- School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, United States
- Eva Vos
- School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, United States
- Dinesh Ravindra Raju
- School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, United States
- Shina Caroline Lynn Kamerlin
- School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, United States
- Remco Sprangers
- Institute of Biophysics and Physical Biochemistry, Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Germany
- Reinhard Sterner
- Institute of Biophysics and Physical Biochemistry, Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Germany
- DOI
-
https://doi.org/10.1021/jacsau.4c00558
- Journal volume & issue
-
Vol. 4,
no. 8
pp.
3258
– 3276
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