Full activation pattern mapping by simultaneous deep brain stimulation and fMRI with graphene fiber electrodes

Siyuan Zhao; Gen Li; Chuanjun Tong; Wenjing Chen; Puxin Wang; Jiankun Dai; Xuefeng Fu; Zheng Xu; Xiaojun Liu; Linlin Lu; Zhifeng Liang; Xiaojie Duan

doi:10.1038/s41467-020-15570-9

Nature Communications (Apr 2020)

Full activation pattern mapping by simultaneous deep brain stimulation and fMRI with graphene fiber electrodes

Siyuan Zhao,
Gen Li,
Chuanjun Tong,
Wenjing Chen,
Puxin Wang,
Jiankun Dai,
Xuefeng Fu,
Zheng Xu,
Xiaojun Liu,
Linlin Lu,
Zhifeng Liang,
Xiaojie Duan

Affiliations

Siyuan Zhao: Department of Biomedical Engineering, College of Engineering, Peking University
Gen Li: Department of Biomedical Engineering, College of Engineering, Peking University
Chuanjun Tong: Institute of Neuroscience, Chinese Academy of Sciences, CAS Center for Excellence in Brain Sciences and Intelligence Technology, Key Laboratory of Primate Neurobiology, Chinese Academy of Sciences
Wenjing Chen: Institute of Neuroscience, Chinese Academy of Sciences, CAS Center for Excellence in Brain Sciences and Intelligence Technology, Key Laboratory of Primate Neurobiology, Chinese Academy of Sciences
Puxin Wang: Department of Biomedical Engineering, College of Engineering, Peking University
Jiankun Dai: Institute of Neuroscience, Chinese Academy of Sciences, CAS Center for Excellence in Brain Sciences and Intelligence Technology, Key Laboratory of Primate Neurobiology, Chinese Academy of Sciences
Xuefeng Fu: Department of Biomedical Engineering, College of Engineering, Peking University
Zheng Xu: Department of Biomedical Engineering, College of Engineering, Peking University
Xiaojun Liu: Department of Biomedical Engineering, College of Engineering, Peking University
Linlin Lu: Department of Biomedical Engineering, College of Engineering, Peking University
Zhifeng Liang: Institute of Neuroscience, Chinese Academy of Sciences, CAS Center for Excellence in Brain Sciences and Intelligence Technology, Key Laboratory of Primate Neurobiology, Chinese Academy of Sciences
Xiaojie Duan: Department of Biomedical Engineering, College of Engineering, Peking University

DOI: https://doi.org/10.1038/s41467-020-15570-9
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 12

Abstract

Read online

Combination of fMRI and deep brain stimulation (DBS) allows for large-scale mapping of brain responses to DBS. Here the authors develop highly MRI compatible graphene fiber electrodes for full brain activation pattern mapping under DBS in Parkinsonian rats.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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