ADS024, a single-strain live biotherapeutic product of Bacillus velezensis alleviates dextran sulfate-mediated colitis in mice, protects human colonic epithelial cells against apoptosis, and maintains epithelial barrier function

• Sophie Irwin,
• Andrea Chupina Estrada,
• Becca Nelson,
• Ashlen Bullock,
• Berkeley Limketkai,
• Wendy Ho,
• Susan Acton,
• Laurent Chesnel,
• Hon Wai Koon

Affiliations

Sophie Irwin

Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, United States

Andrea Chupina Estrada

Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, United States

Becca Nelson

Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, United States

Ashlen Bullock

Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, United States

Berkeley Limketkai

Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, United States

Wendy Ho

Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, United States

Susan Acton

Adiso Therapeutics Inc., Concord, MA, United States

Laurent Chesnel

Adiso Therapeutics Inc., Concord, MA, United States

Hon Wai Koon

Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, United States