Myxoid intravascular papillary endothelial hyperplasia of the hard palate. A unique case?

Abstract

Intravascular papillary endothelial hyperplasia (IPEH) is an uncommon reactive lesion that shares some features with, and thus can be misdiagnosed as, hemangiosarcoma. Most are associated with a thrombus. Oral cases are rare, only 105 being reported through 2020, and only one has been reported in the hard palate. The stroma of the papillary structures has been described as fibrous, hyalinized, or hypocellular and hyalinized. Presented here is a case of IPEH of the hard palate with no associated thrombus and a myxoid stroma of the papillary structures and wall. The significance of the myxoid stroma is that it has the potential to confound the diagnosis and, by analogy to odontogenic and other myxomas, for concern regarding a tendency to recur.

Keywords

• Hard palate
• IPEH
• Masson's tumor
• Myxoid stroma
• Oral mucosa