Confined placental mosaicism of trisomy 6 detected through genome‐wide NIPT was associated with placental abruption

Abstract

Abstract Confined placental mosaicism (CPM) leads to discordant noninvasive prenatal testing (NIPT) results. We describe a very rare case of CPM of trisomy 6 detected through genome‐wide NIPT. This case was associated with placental abruption, which might suggest an association between certain types of CPM detected by NIPT and pregnancy complications.

Keywords

• cell‐free DNA
• confined placental mosaicism
• noninvasive prenatal testing
• placental abruption
• trisomy 6