Prospects for neuroretinoprotective therapy of glaucoma

Abstract

The results of present-day research into the pathogenesis of glaucoma as a neurodegenerative disease, leave no doubt that neuroprotective therapy of the condition is needed. It has been proven that achieving the target intraocular pressure does not always lead to the stabilization of the glaucoma process, as evidenced by a further decrease in visual functions and the death of retinal ganglion cells. Currently, research is focused on finding new drugs that can slow down the damage to the nerve fibers of the optic nerve and prevent apoptotic neuronal death. This literature review presents the results of recent experimental and clinical studies of the most promising neuroprotective drugs.

Keywords

• glaucoma
• neuroprotection
• glaucomatous optic neuropathy