High grade primary leiomyosarcoma of the mandible: case report and literature review

Abstract

Leiomyosarcoma is a rare tumor derived from smooth muscle cells. Oral cavity location is uncommon and represents less than 1%. Only few cases were described in the mandible. Clinical and radiological findings are not specific. Diagnosis is based to histology. The main treatment is surgery and prognosis depend of the quality of resection. We report a clinical case of 33-year-old-woman with a month history of swelling in the left mandible. Computed tomography revealed an extensive lesion involving the left mandibular angle. Surgery with clear margins was not possible and chemotherapy followed by radiotherapy was given. The aim of this work is to review literature concerning this rare malignancy and discuss incidence, histology and treatment approaches.

Keywords

• leiomyosarcoma
• mandible
• head and neck sarcomas
• incidence
• histology
• treatment