Advancements in SERS‐based biological detection and its application and perspectives in pancreatic cancer

Lei Xu; Yujiao Xie; Jie Lin; Aiguo Wu; Tianan Jiang

doi:10.1002/VIW.20230070

View (Feb 2024)

Advancements in SERS‐based biological detection and its application and perspectives in pancreatic cancer

Lei Xu,
Yujiao Xie,
Jie Lin,
Aiguo Wu,
Tianan Jiang

Affiliations

Lei Xu: Department of Ultrasound Medicine The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang China
Yujiao Xie: Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology Zhejiang International Cooperation Base of Biomedical Materials Technology and Application Chinese Academy of Sciences (CAS) Key Laboratory of Magnetic Materials and Devices Ningbo Cixi Institute of Biomedical Engineering Zhejiang Engineering Research Center for Biomedical Materials Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences Ningbo China
Jie Lin: Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology Zhejiang International Cooperation Base of Biomedical Materials Technology and Application Chinese Academy of Sciences (CAS) Key Laboratory of Magnetic Materials and Devices Ningbo Cixi Institute of Biomedical Engineering Zhejiang Engineering Research Center for Biomedical Materials Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences Ningbo China
Aiguo Wu: Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology Zhejiang International Cooperation Base of Biomedical Materials Technology and Application Chinese Academy of Sciences (CAS) Key Laboratory of Magnetic Materials and Devices Ningbo Cixi Institute of Biomedical Engineering Zhejiang Engineering Research Center for Biomedical Materials Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences Ningbo China
Tianan Jiang: Department of Ultrasound Medicine The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang China

DOI: https://doi.org/10.1002/VIW.20230070
Journal volume & issue: Vol. 5, no. 1
pp. n/a – n/a

Abstract

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Abstract Surface‐enhanced Raman spectroscopy (SERS) has become an essential bio‐detection technique. Due to its high sensitivity, good signal specificity, and resistance to photobleaching, SERS has been widely used in biomedical research fields such as molecular imaging, tumor diagnosis, and drug monitoring. This review focuses on the progress of SERS in biomedical applications. We first introduce the basic principle of SERS and the progress of substrate research. Then, we summarize the latest research progress on SERS in drug monitoring, cell and exosome detection, tumor imaging, and detection platforms combining microfluidic and lateral flow technologies. Subsequently, the applied research of SERS in early diagnosis of pancreatic cancer and drug efficacy monitoring is described. Finally, the future development direction and possible challenges of SERS in tumor diagnosis and treatment are proposed.

Published in View

ISSN: 2688-3988 (Print); 2688-268X (Online)
Publisher: Wiley
Country of publisher: Australia
LCC subjects: Technology: Chemical technology: Biotechnology; Medicine: Medicine (General): Medical technology
Website: https://onlinelibrary.wiley.com/journal/2688268x

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Abstract

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