Oral third-generation cephalosporins in the treatment of community-acquired urinary tract infections

Abstract

Cephalosporins are one of the most commonly used antimicrobials for the treatment of variety of bacterial infections. Prudent use of the third-generation cephalosporins is important for the control of spread of cephalosporin-resistant Gram-negative bacteria, especially ESBL-producing Enterobacterales strains. One of the therapeutic areas where the balance between the clinical efficacy and antimicrobial resistance is of critical importance for cephalosporins is urinary tract infections. Current review summarizes existing data on the use of oral third-generation cephalosporins in the treatment of urinary tract infections with a special emphasis to the microbiological data.

Keywords

• urinary tract infections
• acute cystitis
• acute pyelonephritis
• cefixime
• cephalosporins