Associations Between High Plasma Methylxanthine Levels, Sleep Disorders and Polygenic Risk Scores of Caffeine Consumption or Sleep Duration in a Swiss Psychiatric Cohort

• Nermine Laaboub,
• Mehdi Gholam,
• Guibet Sibailly,
• Jennifer Sjaarda,
• Aurélie Delacrétaz,
• Aurélie Delacrétaz,
• Céline Dubath,
• Claire Grosu,
• Marianna Piras,
• Nicolas Ansermot,
• Severine Crettol,
• Frederik Vandenberghe,
• Carole Grandjean,
• Franziska Gamma,
• Murielle Bochud,
• Armin von Gunten,
• Kerstin Jessica Plessen,
• Philippe Conus,
• Chin B. Eap,
• Chin B. Eap,
• Chin B. Eap,
• Chin B. Eap

Affiliations

Nermine Laaboub

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Mehdi Gholam

Center of Psychiatric Epidemiology and Psychopathology, Department of Psychiatry, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Guibet Sibailly

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Jennifer Sjaarda

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Aurélie Delacrétaz

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Aurélie Delacrétaz

Les Toises Psychiatry and Psychotherapy Center, Lausanne, Switzerland

Céline Dubath

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Claire Grosu

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Marianna Piras

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Nicolas Ansermot

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Severine Crettol

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Frederik Vandenberghe

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Carole Grandjean

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Franziska Gamma

Les Toises Psychiatry and Psychotherapy Center, Lausanne, Switzerland

Murielle Bochud

Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland

Armin von Gunten

Service of Old Age Psychiatry, Department of Psychiatry, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Kerstin Jessica Plessen

Service of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Philippe Conus

Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Chin B. Eap

Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland

Chin B. Eap

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland

Chin B. Eap

Center for Research and Innovation in Clinical Pharmaceutical Sciences, University of Lausanne, Lausanne, Switzerland

Chin B. Eap

0Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, University of Lausanne, Geneva, Switzerland