Nature Communications (Mar 2017)
Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness
- Stefanie Heilmann-Heimbach,
- Christine Herold,
- Lara M. Hochfeld,
- Axel M. Hillmer,
- Dale R. Nyholt,
- Julian Hecker,
- Asif Javed,
- Elaine G. Y. Chew,
- Sonali Pechlivanis,
- Dmitriy Drichel,
- Xiu Ting Heng,
- Ricardo C. -H. del Rosario,
- Heide L. Fier,
- Ralf Paus,
- Rico Rueedi,
- Tessel E. Galesloot,
- Susanne Moebus,
- Thomas Anhalt,
- Shyam Prabhakar,
- Rui Li,
- Stavroula Kanoni,
- George Papanikolaou,
- Zoltán Kutalik,
- Panos Deloukas,
- Michael P. Philpott,
- Gérard Waeber,
- Tim D. Spector,
- Peter Vollenweider,
- Lambertus A. L. M. Kiemeney,
- George Dedoussis,
- J. Brent Richards,
- Michael Nothnagel,
- Nicholas G. Martin,
- Tim Becker,
- David A. Hinds,
- Markus M. Nöthen
Affiliations
- Stefanie Heilmann-Heimbach
- Institute of Human Genetics, University of Bonn
- Christine Herold
- German Center for Neurodegenerative Disorders
- Lara M. Hochfeld
- Institute of Human Genetics, University of Bonn
- Axel M. Hillmer
- Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore
- Dale R. Nyholt
- Institute of Health and Biomedical Innovation, Queensland University of Technology
- Julian Hecker
- Institute of Genomic Mathematics, University of Bonn
- Asif Javed
- Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore
- Elaine G. Y. Chew
- Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore
- Sonali Pechlivanis
- Institute of Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-Essen
- Dmitriy Drichel
- Cologne Center for Genomics, University of Cologne
- Xiu Ting Heng
- Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore
- Ricardo C. -H. del Rosario
- Computational and Systems Biology, Genome Institute of Singapore
- Heide L. Fier
- Institute of Genomic Mathematics, University of Bonn
- Ralf Paus
- Dermatology Research Centre, Institute of Inflammation and Repair, University of Manchester
- Rico Rueedi
- Department of Computational Biology, University of Lausanne
- Tessel E. Galesloot
- Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical Center
- Susanne Moebus
- Institute of Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-Essen
- Thomas Anhalt
- Institute of Human Genetics, University of Bonn
- Shyam Prabhakar
- Computational and Systems Biology, Genome Institute of Singapore
- Rui Li
- Departments of Medicine, Centre for Clinical Epidemiology, Genetics and Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University
- Stavroula Kanoni
- William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London
- George Papanikolaou
- Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University
- Zoltán Kutalik
- Swiss Institute of Bioinformatics
- Panos Deloukas
- William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London
- Michael P. Philpott
- Centre for Cell Biology and Cutaneous Research Barts and The London School of Medicine and Dentistry, Queen Mary University of London
- Gérard Waeber
- Department of Internal Medicine, Lausanne University Hospital (CHUV)
- Tim D. Spector
- Department of Twin Research & Genetic Epidemiology, King's College London
- Peter Vollenweider
- Department of Internal Medicine, Lausanne University Hospital (CHUV)
- Lambertus A. L. M. Kiemeney
- Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical Center
- George Dedoussis
- Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University
- J. Brent Richards
- Departments of Medicine, Centre for Clinical Epidemiology, Genetics and Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University
- Michael Nothnagel
- Cologne Center for Genomics, University of Cologne
- Nicholas G. Martin
- QIMR Berghofer Medical Research Institute
- Tim Becker
- Institute for Community Medicine, Ernst Moritz Arndt University Greifswald
- David A. Hinds
- 23andMe Inc.
- Markus M. Nöthen
- Institute of Human Genetics, University of Bonn
- DOI
- https://doi.org/10.1038/ncomms14694
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 8
Abstract
Male-pattern baldness is a common condition in which hair is progressively lost from the scalp. Here, the authors find 23 new genetic variants associated with this condition and suggest that it is not an isolated trait but may share an underlying biological basis with various diseases.
