Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activitieslammatory activitiesretain-->

Abstract

Two new compounds, named lyciumlignan D (1) and lyciumphenyl propanoid A (2), along with seven known compounds, were isolated from the root bark of Lycium chinense. Their structures were elucidated using spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR, CD), as well as by comparison with those of the literature. Compounds 39 were isolated from this genus for the first time. In the in vitro assay, compounds 3, 6, and 7 exhibited stronger anti-inflammatory effects than the positive control curcumin at a concentration of 10 μmol/L.

Keywords

• Lycium chinense
• Lyciumlignan D
• Lyciumphenyl propanoid A
• Structure elucidation
• Anti-inflammatory effect