Local Immunity Status and Inflammation Markers in Patients with Endogenous Uveitis

Abstract

In patients with uveitis of infectious etiology, a significant increase in the index of intoxication and acute inflammation (the Leukocyte Intoxication Index -LII), by 3.4 times on average, was observed. At the same time, this increase in the LII index, in our opinion, was due to the decrease in the percentage of eosinophils in the blood, which in turn increased the number of segmented neutrophils and a decrease in the number of lymphocytes. Rheumatic uveitis and systemic disease were accompanied by a significant increase in the IgE levels, not only in the serum, by 2.9 times, on average, but in the LF as well, by 3.5 times, on average. This study revealed that endogenous uveitis of infectious etiology is characterized by high levels of the Leukocyte Intoxication Index and Sensitization Index in the lacrimal fluid.

Keywords

• endogenous uveitis
• inflammation markers.