Сеченовский вестник (Dec 2022)
RETRACTED: EVIDENCE OF ANCIENT HIV-1 TRANSMISSION IN THE NORTHERN EUROPE. PALAEOEPIDEMIOLOGICAL ANALYSIS
Abstract
RETRACTED ARTICLELongitudinal co-evolution of human beings and pathogens resulted in polymorphism of Homo sapiens. CCR5Δ32 HIV-resistance allele is the exception to the rules. Recent origin of HIV-1 in Africa contradicted with the appearance of CCR5Δ32 allele in Northern Europe in previous ages. The author proposed non-contradictory theory of primary appearance of ancient HIV-1 in the Northern Europe 7–10 thousand years ago. The primary epidemics of HIV-infection had been stopped by the appearance of CCR5Δ32 mutation among the affected population. Reemergence of HIV-1 nowadays resulted by the penetration of hibernated HIV-1 into population of drug addicts and men having sex with men.