Periodontitis and Cardiovascular Diseases. Consensus Report
M. Sanz,
A. Marco del Castillo,
S. Jepsen,
J. R. Gonzalez-Juanatey,
F. D’Aiuto,
P Bouchard,
I. Chapple,
T. Dietrich,
I. Gotsman,
F. Graziani,
D. Herrera,
B. Loos,
P. Madianos,
J. B. Michel,
P. Perel,
B. Pieske,
L. Shapira,
M. Schechter,
M. Tonetti,
C. Vlachopoulos,
G. Wimmer
Affiliations
M. Sanz
Department of Dental Clinical Specialties and ETEP Research Group, Faculty of Odontology, University Complutense of Madrid, Plaza Ramon y Cajal, Madrid
A. Marco del Castillo
Cardiology Department, Hospital Universitario Ramon y Cajal, Madrid
S. Jepsen
Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn
J. R. Gonzalez-Juanatey
Cardiology Department, University Hospital, University of Santiago de Compostela, IDIS, CIBERCV
F. D’Aiuto
Department of Periodontology, Eastman Dental Institute and Hospital, University College London, London
P Bouchard
U.F.R. d’odontologie, Université Paris Diderot, Hôpital Rothschild AP-HP, Paris
I. Chapple
School of Dentistry, Institute of Clinical Sciences, College of Medical and Dental Sciences, The University of Birmingham, Birmingham
T. Dietrich
School of Dentistry, Institute of Clinical Sciences, College of Medical and Dental Sciences, The University of Birmingham, Birmingham
I. Gotsman
Heart Institute, Hadassah University Hospital, Jerusalem
F. Graziani
Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa
D. Herrera
Department of Dental Clinical Specialties and ETEP Research Group, Faculty of Odontology, University Complutense of Madrid, Plaza Ramon y Cajal, Madrid
B. Loos
ACTA University, Amsterdam
P. Madianos
Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens
J. B. Michel
Inserm Unit 1148, laboratory for translational CV science, X. Bichat hospital, Paris
P. Perel
World Heart Federation, Geneva, CH; Centre for Global Chronic Conditions, London School of Hygiene and Tropical Medicine
B. Pieske
Charité Universitätsmedizin Berlin, Department of Internal Medicine and Cardiology, Berlin, DE; DZHK (German Center for Cardiovascular Research) Partnersite Berlin, German Heart Institut Berlin
L. Shapira
Department of Periodontology, Hebrew University – Hadassah Faculty of Dental Medicine, Jerusalem
M. Schechter
Leviev Heart Center, Chaim Sheba Medical Center, tel Hashomer and the Sackler Faculty of Medicine, Tel Aviv University
M. Tonetti
Department of Periodontology, The University of Hong Kong, Prince Philip Dental Hospital
C. Vlachopoulos
Department of Cardiology, National and Kapodistrian University of Athens
G. Wimmer
Department of Prosthetic Dentistry, School of Dental Medicine, Karl-Franzens University Graz
Background: In Europe cardiovascular disease (CVD) is responsible for 3.9 million deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to heart failure) the major cause of these CVD related deaths. Periodontitis is also a chronic non‐communicable disease (NCD) with a high prevalence, being severe periodontitis, affecting 11.2% of the world’s population, the sixth most common human disease. Material and Methods: There is now a significant body of evidence to support independent associations between severe periodontitis and several NCDs, in particular CVD. In 2012 a joint workshop was held between the European Federation of Periodontology (EFP) and the American Academy of Periodontology to review the literature relating periodontitis and systemic diseases, including CVD. In the last five years important new scientific information has emerged providing important emerging evidence to support these associations. Results and Conclusions: The present review reports the proceedings of the workshop jointly organised by the EFP and the World Heart Federation (WHF), which has updated the existing epidemiological evidence for significant associations between periodontitis and CVD, the mechanistic links and the impact of periodontal therapy on cardiovascular and surrogate outcomes. This review has also focused on the potential risk and complications of periodontal therapy in patients on anti thrombotic therapy and has made recommendations for dentists, physicians and for patients visiting both the dental and medical practices.
