Frontiers in Pediatrics (Mar 2024)
Cardiac injury progression in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection: a review
- Song Su,
- Song Su,
- Wandong Hu,
- Wandong Hu,
- Xiao Chen,
- Xiao Chen,
- Ying Ren,
- Ying Ren,
- Yi Lu,
- Yi Lu,
- Jianguo Shi,
- Jianguo Shi,
- Tong Zhang,
- Tong Zhang,
- Huan Zhang,
- Huan Zhang,
- Meng Wang,
- Meng Wang,
- Yaping Wang,
- Yaping Wang,
- Fen Zhao,
- Fen Zhao,
- Ruifeng Jin,
- Ruifeng Jin,
- Yong Liu,
- Yong Liu,
- Hongwei Zhang,
- Hongwei Zhang,
- Guohua Liu,
- Guohua Liu
Affiliations
- Song Su
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Song Su
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Wandong Hu
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Wandong Hu
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Xiao Chen
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Xiao Chen
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Ying Ren
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Ying Ren
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Yi Lu
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Yi Lu
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Jianguo Shi
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Jianguo Shi
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Tong Zhang
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Tong Zhang
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Huan Zhang
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Huan Zhang
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Meng Wang
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Meng Wang
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Yaping Wang
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Yaping Wang
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Fen Zhao
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Fen Zhao
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Ruifeng Jin
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Ruifeng Jin
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Yong Liu
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Yong Liu
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Hongwei Zhang
- Epilepsy Center, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Hongwei Zhang
- Epilepsy Center, Jinan Children's Hospital, Jinan, Shandong, China
- Guohua Liu
- Department of Ophthalmology, Children's Hospital Affiliated to Shandong University, Jinan, Shandong, China
- Guohua Liu
- Department of Ophthalmology, Jinan Children's Hospital, Jinan, Shandong, China
- DOI
- https://doi.org/10.3389/fped.2024.1348016
- Journal volume & issue
-
Vol. 12
Abstract
The symptoms and signs of infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are milder in children than in adults. However, in April 2020, British pediatricians first reported that coronavirus disease 2019 (COVID-19) may present as multisystem inflammatory syndrome in children and adolescents (MIS-C), similar to that observed in Kawasaki disease. MIS-C can be associated with multiple systemic injuries and even death in children. In addition to digestive system involvement, cardiac injury is prominent. This article reviews the pathogenesis, clinical manifestations, and treatment of cardiac injury caused by MIS-C, which may help clinicians in early diagnosis and timely commencement of treatment.
Keywords
- severe acute respiratory syndrome coronavirus 2
- children
- multisystem inflammatory syndrome
- cardiac injury
- coronavirus disease 2019
