A Secreted NlpC/P60 Endopeptidase from Photobacterium damselae subsp.
<i>piscicida</i>
Cleaves the Peptidoglycan of Potentially Competing Bacteria

Johnny Lisboa; Cassilda Pereira; Aline Rifflet; Juan Ayala; Mateus S. Terceti; Alba V. Barca; Inês Rodrigues; Pedro José Barbosa Pereira; Carlos R. Osorio; Francisco García-del Portillo; Ivo Gomperts Boneca; Ana do Vale; Nuno M. S. dos Santos

doi:10.1128/mSphere.00736-20

mSphere (Feb 2021)

A Secreted NlpC/P60 Endopeptidase from Photobacterium damselae subsp. <i>piscicida</i> Cleaves the Peptidoglycan of Potentially Competing Bacteria

Johnny Lisboa,
Cassilda Pereira,
Aline Rifflet,
Juan Ayala,
Mateus S. Terceti,
Alba V. Barca,
Inês Rodrigues,
Pedro José Barbosa Pereira,
Carlos R. Osorio,
Francisco García-del Portillo,
Ivo Gomperts Boneca,
Ana do Vale,
Nuno M. S. dos Santos

Affiliations

Johnny Lisboa: ORCiD; Fish Immunology and Vaccinology Group, Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal
Cassilda Pereira: Fish Immunology and Vaccinology Group, Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal
Aline Rifflet: Institut Pasteur, Unité Biologie et Génétique de la Paroi Bactérienne, Paris, France
Juan Ayala: Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
Mateus S. Terceti: Departamento de Microbioloxía e Parasitoloxía, Instituto de Acuicultura, Universidade de Santiago de Compostela, Santiago de Compostela, Spain
Alba V. Barca: Departamento de Microbioloxía e Parasitoloxía, Instituto de Acuicultura, Universidade de Santiago de Compostela, Santiago de Compostela, Spain
Inês Rodrigues: Fish Immunology and Vaccinology Group, Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal
Pedro José Barbosa Pereira: ORCiD; Biomolecular Structure Group, Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal
Carlos R. Osorio: ORCiD; Departamento de Microbioloxía e Parasitoloxía, Instituto de Acuicultura, Universidade de Santiago de Compostela, Santiago de Compostela, Spain
Francisco García-del Portillo: ORCiD; Laboratorio de Patógenos Bacterianos Intracelulares, Centro Nacional de Biotecnología (CNB), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
Ivo Gomperts Boneca: Institut Pasteur, Unité Biologie et Génétique de la Paroi Bactérienne, Paris, France
Ana do Vale: Fish Immunology and Vaccinology Group, Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal
Nuno M. S. dos Santos: Fish Immunology and Vaccinology Group, Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal

DOI: https://doi.org/10.1128/mSphere.00736-20
Journal volume & issue: Vol. 6, no. 1

Abstract

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Peptidoglycan (PG) is a major component of the bacterial cell wall formed by long chains of two alternating sugars interconnected by short peptides, generating a mesh-like structure that enwraps the bacterial cell. Although PG provides structural integrity and support for anchoring other components of the cell envelope, it is constantly being remodeled through the action of specific enzymes that cleave or join its components.

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

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