Single Residue on the WPD-Loop Affects the pH Dependency of Catalysis in Protein Tyrosine Phosphatases

• Ruidan Shen,
• Rory M. Crean,
• Sean J. Johnson,
• Shina C. L. Kamerlin,
• Alvan C. Hengge

Affiliations

Ruidan Shen

Department of Chemistry and Biochemistry, Utah State University, Logan, Utah, United States

Rory M. Crean

Science for Life Laboratory, Department of Chemistry − BMC, Uppsala University, Uppsala, Sweden

Sean J. Johnson

Department of Chemistry and Biochemistry, Utah State University, Logan, Utah, United States

Shina C. L. Kamerlin

Science for Life Laboratory, Department of Chemistry − BMC, Uppsala University, Uppsala, Sweden

Alvan C. Hengge

Department of Chemistry and Biochemistry, Utah State University, Logan, Utah, United States