Communications Biology (Aug 2021)

Vaginal microbiome Lactobacillus crispatus is heritable among European American women

  • Michelle L. Wright,
  • Jennifer M. Fettweis,
  • Lindon J. Eaves,
  • Judy L. Silberg,
  • Michael C. Neale,
  • Myrna G. Serrano,
  • Nicole R. Jimenez,
  • Elizabeth Prom-Wormley,
  • Philippe H. Girerd,
  • Joseph F. Borzelleca,
  • Kimberly K. Jefferson,
  • Jerome F. Strauss,
  • Timothy P. York,
  • Gregory A. Buck

DOI
https://doi.org/10.1038/s42003-021-02394-6
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 6

Abstract

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Wright et al. apply biometric genetic approach to identify the extent to which host genetic factors influence species-level variation in the vaginal microbiota. Their study suggests that Lactobacillus crispatus, a major determinant of vaginal health, is heritable among European American women, consistent with the reduced prevalence of adverse reproductive disorders in them.