Nature Communications (Feb 2023)

A molecular atlas reveals the tri-sectional spinning mechanism of spider dragline silk

  • Wenbo Hu,
  • Anqiang Jia,
  • Sanyuan Ma,
  • Guoqing Zhang,
  • Zhaoyuan Wei,
  • Fang Lu,
  • Yongjiang Luo,
  • Zhisheng Zhang,
  • Jiahe Sun,
  • Tianfang Yang,
  • TingTing Xia,
  • Qinhui Li,
  • Ting Yao,
  • Jiangyu Zheng,
  • Zijie Jiang,
  • Zehui Xu,
  • Qingyou Xia,
  • Yi Wang

DOI
https://doi.org/10.1038/s41467-023-36545-6
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 16

Abstract

Read online

The genetic basis of spider major ampullate (Ma) gland silk production remains unknown. Hu et al. unveil a molecular atlas of this gland for the golden orb-weaving spider combining genome assembly and multiomics, revealing the single-cell spatial architecture of silk production in the Ma gland.