Arquivos de Neuro-Psiquiatria (Apr 2025)

Efficacy and safety of glucagon-like peptide 1 agonists for Parkinson's disease: a systematic review and meta-analysis

  • Luis O. S. Nogueira,
  • Roberto A. S. V. Mazetto,
  • Maria L. R. Defante,
  • Vânio L. J. Antunes,
  • Ocílio Ribeiro Gonçalves,
  • Angela Maria Sandini Corso,
  • Marcus V. Della Coletta,
  • Dayany Leonel Boone,
  • Walderico Silva Machado Filho,
  • Vanderci Borges,
  • Henrique Ballalai Ferraz

DOI
https://doi.org/10.1055/s-0045-1806824
Journal volume & issue
Vol. 83, no. 04
pp. 001 – 010

Abstract

Read online

Background Recent research on Parkinson's disease (PD) therapy has highlighted glucagon-like peptide 1 (GLP-1) agonists as potential therapeutic agents. However, recent randomized controlled trials (RCTs) have shown mixed results regarding the use of this medication.

Keywords