Disseminated toxoplasmosis in a heart transplant patient despite co-trimoxazole prophylaxis: A case report

Abstract

We report the case of a 61 year-old male who underwent heart transplantation eight months before developing a systemic condition with central nervous system, lung, kidney, colonic, cutaneous, and hematologic involvement, found to be secondary to a systemic toxoplasmosis despite co-trimoxazole prophylaxis in a previous-to-transplant seronegative patient receiving a heart from a seropositive donor. A review of prophylactic options in our environment is discussed.

Keywords

• Toxoplasmosis
• heart transplantation
• immune tolerance
• seroconversion