BMC Bioinformatics (Apr 2024)

OmicNavigator: open-source software for the exploration, visualization, and archival of omic studies

  • Terrence R. Ernst,
  • John D. Blischak,
  • Paul Nordlund,
  • Joe Dalen,
  • Justin Moore,
  • Akshay Bhamidipati,
  • Pankaj Dwivedi,
  • Joe LoGrasso,
  • Marco Rocha Curado,
  • Brett Warren Engelmann

DOI
https://doi.org/10.1186/s12859-024-05743-4
Journal volume & issue
Vol. 25, no. 1
pp. 1 – 10

Abstract

Read online

Abstract Background The results of high-throughput biology (‘omic’) experiments provide insight into biological mechanisms but can be challenging to explore, archive and share. The scale of these challenges continues to grow as omic research volume expands and multiple analytical technologies, bioinformatic pipelines, and visualization preferences have emerged. Multiple software applications exist that support omic study exploration and/or archival. However, an opportunity remains for open-source software that can archive and present the results of omic analyses with broad accommodation of study-specific analytical approaches and visualizations with useful exploration features. Results We present OmicNavigator, an R package for the archival, visualization and interactive exploration of omic studies. OmicNavigator enables bioinformaticians to create web applications that interactively display their custom visualizations and analysis results linked with app-derived analytical tools, graphics, and tables. Studies created with OmicNavigator can be viewed within an interactive R session or hosted on a server for shared access. Conclusions OmicNavigator can be found at https://github.com/abbvie-external/OmicNavigator

Keywords