Nature Communications (Mar 2023)

PCR-like performance of rapid test with permselective tunable nanotrap

  • Seong Jun Park,
  • Seungmin Lee,
  • Dongtak Lee,
  • Na Eun Lee,
  • Jeong Soo Park,
  • Ji Hye Hong,
  • Jae Won Jang,
  • Hyunji Kim,
  • Seokbeom Roh,
  • Gyudo Lee,
  • Dongho Lee,
  • Sung-Yeon Cho,
  • Chulmin Park,
  • Dong-Gun Lee,
  • Raeseok Lee,
  • Dukhee Nho,
  • Dae Sung Yoon,
  • Yong Kyoung Yoo,
  • Jeong Hoon Lee

DOI
https://doi.org/10.1038/s41467-023-37018-6
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 10

Abstract

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Lateral flow assays are valuable rapid diagnostic tests, but low sensitivity can hinder their precision. Here, the authors report an enrichment method using nanoporous AAO and red blood cell membranes, which when applied to patient samples prior to analysis can improve sensitivity up to 20-fold.