Nature Communications (Mar 2023)
PCR-like performance of rapid test with permselective tunable nanotrap
- Seong Jun Park,
- Seungmin Lee,
- Dongtak Lee,
- Na Eun Lee,
- Jeong Soo Park,
- Ji Hye Hong,
- Jae Won Jang,
- Hyunji Kim,
- Seokbeom Roh,
- Gyudo Lee,
- Dongho Lee,
- Sung-Yeon Cho,
- Chulmin Park,
- Dong-Gun Lee,
- Raeseok Lee,
- Dukhee Nho,
- Dae Sung Yoon,
- Yong Kyoung Yoo,
- Jeong Hoon Lee
Affiliations
- Seong Jun Park
- Department of Electrical Engineering, Kwangwoon University
- Seungmin Lee
- Department of Electrical Engineering, Kwangwoon University
- Dongtak Lee
- School of Biomedical Engineering, Korea University
- Na Eun Lee
- Department of Electrical Engineering, Kwangwoon University
- Jeong Soo Park
- Department of Electrical Engineering, Kwangwoon University
- Ji Hye Hong
- Department of Electrical Engineering, Kwangwoon University
- Jae Won Jang
- School of Biomedical Engineering, Korea University
- Hyunji Kim
- School of Biomedical Engineering, Korea University
- Seokbeom Roh
- Department of Biotechnology and Bioinformatics, Korea University
- Gyudo Lee
- Department of Biotechnology and Bioinformatics, Korea University
- Dongho Lee
- CALTH Inc.
- Sung-Yeon Cho
- Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea
- Chulmin Park
- Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea
- Dong-Gun Lee
- Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea
- Raeseok Lee
- Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea
- Dukhee Nho
- Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea
- Dae Sung Yoon
- School of Biomedical Engineering, Korea University
- Yong Kyoung Yoo
- Department of Electronic Engineering, Catholic Kwandong University
- Jeong Hoon Lee
- Department of Electrical Engineering, Kwangwoon University
- DOI
- https://doi.org/10.1038/s41467-023-37018-6
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 10
Abstract
Lateral flow assays are valuable rapid diagnostic tests, but low sensitivity can hinder their precision. Here, the authors report an enrichment method using nanoporous AAO and red blood cell membranes, which when applied to patient samples prior to analysis can improve sensitivity up to 20-fold.