Haematologica (Jan 2008)

Decrease in the frequency of meningeal involvement in AIDS-related systemic lymphoma in patients receiving HAART

  • José-Tomás Navarro,
  • Ferran Vall-Llovera,
  • José-Luis Mate,
  • Mireia Morgades,
  • Evarist Feliu,
  • Josep-Maria Ribera

DOI
https://doi.org/10.3324/haematol.11767
Journal volume & issue
Vol. 93, no. 1

Abstract

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We evaluated the frequency of primary central nervous system lymphoma and leptomeningeal involvement in systemic non-Hodgkin’s lymphoma (NHL) in HIV-infected patients. Those receiving highly active antiretroviral therapy (HAART) showed a decrease in leptomeningeal involvement in systemic NHL (0/30 vs. 12/87; p=0.023). Therefore HAART could prevent CNS involvement in systemic NHL.