Revista de la Sociedad Argentina de Diabetes (Jun 2019)
PYELONEPHRITIS AND INTERSTITIAL NEPHRITIS
Abstract
Acute pyelonephritis is a frequent infection that can progress to abscess or emphysematous pyelonephritis (EP); most cases are caused by Escherichia coli. The clinical onset can range from mild symptoms to septicemia. The possibility of bacteremia depends on host factors: patients who are seriously ill, immunocompromised, with urinary tract obstruction and > 65 years of age. More than 90% of EP occurs in patients with diabetes. Interstitial nephritis affecting the renal interstitium, can be acute or chronic, in most cases due to NSAIDs or antibiotics. Both pathologies are predominant in women.
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