Nature Communications (Dec 2022)

Functional crosstalk between the cohesin loader and chromatin remodelers

  • Sofía Muñoz,
  • Andrew Jones,
  • Céline Bouchoux,
  • Tegan Gilmore,
  • Harshil Patel,
  • Frank Uhlmann

DOI
https://doi.org/10.1038/s41467-022-35444-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

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Chromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear nucleosomes