Investigations of Structural, Optical, Thermal, and spectroscopic characteristics of CdO-Ni nanoparticles employed in anti-cancer activities for cancer cells

Abstract

In this communication, CdO doped with Ni was employed for new biological applications as an anti-cancer. However, the prepared system needed to be identified through the typical characterizations. The Cd1-xNixO system was utilized by the Co-precipitate calcinations method. To enhance the availability and processability of the materials, and be as sure of achieving the nanomaterials, X-ray diffraction (XRD) analysis indicated exhibited a polycrystalline structure with distinctive structural parameters—however, the single phase Cd1-xNixO exhibits nanoscale material.The optical band gap of the samples was determined using diffused reflectance spectra analysis, revealing Eg values of 2.19 eV for undoped CdO and ranging from 1.62 to 2.12 eV for Ni-doped CdO samples at varying concentrations of Ni.Thermal stability measurements were conducted using a Thermogravimetric analyzer (TGA) in the temperature range from room temperature to 1000 °C at a rate of 15 deg/min. Furthermore, the cytotoxicity effect of the synthesized Cd1-xNixO samples was evaluated against four different cancer cell lines: breast carcinoma (MCF-7), human hepatoblastoma (HepG2), human lung adenocarcinoma (A549), and human breast cancer (MDA-MB-231).Overall, these findings provide valuable insights into the properties of Cd1-xNixO nanostructures synthesized via the Co-precipitate calcinations method and their potential applications in various fields, including optoelectronics and biomedical sciences.

Keywords

• Nanopowder
• Ni doped CdO nano-structure
• XRD
• Diffused reflectance
• Optical constants
• And breast cancer (MDA-MB-231)