Synthesis and Structure of Novel Phenothiazine Derivatives, and Compound Prioritization via In Silico Target Search and Screening for Cytotoxic and Cholinesterase Modulatory Activities in Liver Cancer Cells and In Vivo in Zebrafish
Mehmet Murat Kisla,
Murat Yaman,
Fikriye Zengin-Karadayi,
Busra Korkmaz,
Omer Bayazeid,
Amrish Kumar,
Ravindra Peravali,
Damla Gunes,
Rafed Said Tiryaki,
Emine Gelinci,
Gulcin Cakan-Akdogan,
Zeynep Ates-Alagoz,
Ozlen Konu
Affiliations
Mehmet Murat Kisla
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Ankara, Turkey
Murat Yaman
Interdisciplinary Program in Neuroscience, Bilkent University, Ankara, Turkey
Fikriye Zengin-Karadayi
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Ankara, Turkey
Busra Korkmaz
Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
Omer Bayazeid
Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
Amrish Kumar
Institute of Toxicology and Genetics (ITG), Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, Germany
Ravindra Peravali
Institute of Toxicology and Genetics (ITG), Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, Germany
Damla Gunes
Interdisciplinary Program in Neuroscience, Bilkent University, Ankara, Turkey
Rafed Said Tiryaki
Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
Emine Gelinci
Izmir Biomedicine and Genome Center (IBG), Izmir, Turkey
Gulcin Cakan-Akdogan
Izmir Biomedicine and Genome Center (IBG), Izmir, Turkey
Zeynep Ates-Alagoz
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Ankara, Turkey
Ozlen Konu
Interdisciplinary Program in Neuroscience, Bilkent University, Ankara, Turkey
