Кубанский научный медицинский вестник (Jun 2015)

ENDOTHELIOPROTECTIVE AND CARDIOPROTECTIVE ACTIVITY OF SELECTIVE ARGINASE II INHIBITOR

  • V. I. Yakushev,
  • V. V. Gureev,
  • M. V. Pokrovskii,
  • M. V. Korokin,
  • O. S. Gudyrev,
  • T. G. Pokrovskaya,
  • E. A. Beskhmelnitsyna,
  • A. S. Litvinova,
  • V. V. Elagin

Journal volume & issue
no. 3
pp. 139 – 142

Abstract

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They researched endothelioprotective and cardioprotective activity of arginase II selective inhibitor (substance code ZB49-0010C) in model of L-NAME-induced deficit of nitric oxide. The results of studies of arginase II selective inhibitor (substance code ZB49-0010C) show the presence dose-dependent endothelioprotective and cardioprotective activity, the severity of which sincreases with increasing dose.

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