Introduction: The purpose of this study was to investigate the relationship between the perception of educational justice and awareness of the future of career with the academic enthusiasm of the students of Gonabad University of Medical Sciences. Methods: In this descriptive correlational study the characteristics of perceived educational justice and awareness of the future of career were considered as predictive variables and academic enthusiasm as the criterion variable. The statistical population was all Ph.D., associate and undergraduate students of Gonabad University of Medical Sciences in the academic year of 2017. A sample of 275 people was selected based on randomized, proportional to volume and step by step method. The research instruments were a questionnaire of academic enthusiasm, a questionnaire on knowledge of the future of career and a questionnaire on perceived educational justice. For analyzing data, multivariate regression and Pearson correlation coefficient were used. Result: The results of regression analysis indicated that 16% of the changes in the variance of academic enthusiasm scores with prediction of educational justice and awareness of the career future were predictable. The results of Pearson correlation coefficient showed that there was a relationship between academic enthusiasm and perception of educational justice (P <0.01) and knowledge of the career future (P <0.01). Conclusion: The results of the study indicated that there was a perception of educational justice and awareness of the career future with the academic enthusiasm of the students of the Gonabad University of Medical Sciences. These results showed that having a positive perception of educational justice and knowledge about the future of career of medical students could improve their academic enthusiasm. Therefore, it is suggested that educational managers of the Universities of Medical Sciences should pay attention to educational justice and awareness of the career future of the students and increase their interest and enthusiasm to education. Keywords: Perceived educational justice, Awareness of the career future, Academic Enthusiasm.