Migration paths of cells different origins in the embryonic human heart

Abstract

Hearts of human embryos were investigated using immunohistochemical method with antibodies to neurofilaments from 4 to 8 week of prenatal development. It was found that the embryonic human heart there are NF-positive cells, which occupy its territory by two mechanisms: through the migration of intercellular spaces and on the mechanism immersion out of heart cavity. In the second case neurofilaments-positive cells through the endothelium of blood vessels or endocardium immersion into the myocardium or mesenchymal areas. Mesenchyme in the heart contain neurofilamentpositive cells, migrating here from both mechanisms. Similar cells have been found by us in the liver of human embryo, beginning at 5 weeks of prenatal development.

Keywords

• myocardium
• neurofilaments
• blood cells
• migration
• embryonic human heart