Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul (Jan 2009)
COMPARISON OF ANALGESIA DURATION, NAUSEA AND VOMITING BETWEEN MARCAINE AND BUPRENORPHINE WITH BUPIVACAINE ALONE IN SPINAL ANESTHESIA
Abstract
BACKGROUND AND OBJECTIVE: Pain, nausea and vomiting are the most common problems in patients in recovery room and after leaving the recovery room. The aim of this study was to determine the duration of analgesia and its complications after using bupivacaine and lidocaine with buprenorphine and bupivacaine alone.METHODS: This clinical trial study was performed on 187 patients aged 16-60 years old who referred for herniorrhaphy or lower limb orthopedic surgery to the hospitals of Babol city. Patients were divided into three groups including first group received lidocaine 2cc (5%) with buprenorphine 50 µg, second group received bupivacaine 2cc (5%) with buprenorphine 50 µg and third group received bupivacaine 2cc (5%) alone. Data including age, sex, duration of analgesia according to visual-analogue score, nausea and vomiting, and itching and urinary retention complications were recorded.FINDINGS: The results showed that the mean time that pain began was significantly more in patients receiving bupivacaine with buprenorphine (8 hours) than those receiving lidocaine and buprenorphine (5.8 hours) and bupivacaine alone (4 hours) (p<0.001). Also the time for analgesia treatment of severe pain was significantly higher in bupivacaine with buprenorphine group (10.8 hours) than other groups (7.9 and 6.3 hours) (p<0.001). The rate of nausea and vomiting was not significantly different between groups but itching and urinary retention was more common in group received bupivacaine with buprenorphine than other groups (p<0.05). CONCLUSION: Results showed using bupivacaine with buprenorphine causes longer duration of analgesia. Therefore it is recommended to use it for spinal anesthesia.
