Evaluation of Infections in Hospitalised Pregnant Women

Abstract

Introduction: Hormonal and immunological changes in pregnancy may lead to an increase in infectious diseases caused by some pathogens. In this study, we aimed to determine the types of infections and treatment approaches in pregnant women who were hospitalized due to infectious diseases. Materials and Methods: This retrospective study included 87 pregnant women who were hospitalized in the Infectious Diseases and Clinical Microbiology and Obstetrics and Gynecology Clinics of the University of Health Sciences, Ankara Numune Training and Research Hospital between January 2011 and December 2016. Results: The median age of the 87 pregnant women was 23 years, and 40 of them were in the second trimester. Analysis of infection diagnoses showed that urinary tract infection (UTI) was the most common infection (59 patients, 67.8%). Most of the patients with UTI developed pyelonephritis (42 patients, 71.1%). Twenty-five patients" urine culture yielded a pathogen in urine culture while Escherichia coli was the most common isolate. Seven of the isolated strains were extended-spectrum beta-lactamase (ESBL) producers. Ceftriaxone was started in 35 of the patients with pyelonephritis. Treatment duration was 5-17 days (mean 11 days). Other infections were acute gastroenteritis, pneumonia, influenza, varicella, measles, tularemia, brucellosis, Crimean-Congo hemorrhagic fever, adult-onset Still"s disease, acute viral hepatitis A and B coinfection, and perianal abscess. Conclusion: UTI is the most common infection in pregnant women. E. coli is the most commonly isolated microorganism and the rate of ESBLpositive isolates is increasing. Pyelonephritis is more common than other UTI and requires hospitalization.

Keywords

• Pregnancy
• urinary system infection
• brucellosis
• CCHF
• ESBL