Supporting data on in vitro cardioprotective and proliferative paracrine effects by the human amniotic fluid stem cell secretome
Carolina Balbi,
Kirsten Lodder,
Ambra Costa,
Silvia Moimas,
Francesco Moccia,
Tessa van Herwaarden,
Vittorio Rosti,
Francesca Campagnoli,
Agnese Palmeri,
Pierangela De Biasio,
Francesco Santini,
Mauro Giacca,
Marie-Josè Goumans,
Lucio Barile,
Anke M. Smits,
Sveva Bollini
Affiliations
Carolina Balbi
Regenerative Medicine Laboratory, Department of Experimental Medicine, University of Genova, Genova, Italy; Molecular and Cell Cardiology Laboratory, CardioCentro Ticino, Lugano, Switzerland
Kirsten Lodder
Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands
Ambra Costa
Regenerative Medicine Laboratory, Department of Experimental Medicine, University of Genova, Genova, Italy
Silvia Moimas
Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy
Francesco Moccia
General Physiology Laboratory, Department of Biology and Biotechnology “Lazzaro Spallanzani”, University of Pavia, Pavia, Italy
Tessa van Herwaarden
Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands
Vittorio Rosti
Laboratory of Biochemistry, Biotechnology and Advanced Diagnostic, Myelofibrosis Study Centre, IRCCS Ospedale Policlinico San Matteo, Pavia, Italy
Francesca Campagnoli
Regenerative Medicine Laboratory, Department of Experimental Medicine, University of Genova, Genova, Italy
Agnese Palmeri
Dept. of Obstetrics and Gynecology, Ospedale Policlinico San Martino - IRCCS per l’Oncologia, Genova, Italy
Pierangela De Biasio
Dept. of Obstetrics and Gynecology, Ospedale Policlinico San Martino - IRCCS per l’Oncologia, Genova, Italy
Francesco Santini
Division of Cardiac Surgery, Ospedale Policlinico San Martino - IRCCS per l’Oncologia, Genova, Italy
Mauro Giacca
Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy
Marie-Josè Goumans
Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands
Lucio Barile
Molecular and Cell Cardiology Laboratory, CardioCentro Ticino, Lugano, Switzerland
Anke M. Smits
Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands
Sveva Bollini
Regenerative Medicine Laboratory, Department of Experimental Medicine, University of Genova, Genova, Italy; Corresponding author. Department of Experimental Medicine, University of Genova, 16132, Genova, Italy.
The data and information presented here refer to the research article entitled: “Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting with the human amniotic fluid stem cell secretome” (Balbi et al., 2019, Apr 04). This dataset illustrates the in vitro paracrine effect exerted by the human amniotic fluid stem cell secretome on rodent neonatal cardiomyocytes, human endothelial progenitors and different subsets of cardiac progenitor cells. Cytokine/chemokine profiling of the human amniotic fluid stem cell secretome is provided as well. This data can provide useful insights in regenerative medicine as demonstrating the in vitro cardioprotective and proliferative secretory paracrine potential of human fetal stem cells. Keywords: Paracrine effect, Human amniotic fluid stem cells, Cardiac progenitor cells, Neonatal cardiomyocytes, Endothelial progenitors, Proliferation, Cardioprotection, Angiogenesis
