Data in Brief (Aug 2019)

Supporting data on in vitro cardioprotective and proliferative paracrine effects by the human amniotic fluid stem cell secretome

  • Carolina Balbi,
  • Kirsten Lodder,
  • Ambra Costa,
  • Silvia Moimas,
  • Francesco Moccia,
  • Tessa van Herwaarden,
  • Vittorio Rosti,
  • Francesca Campagnoli,
  • Agnese Palmeri,
  • Pierangela De Biasio,
  • Francesco Santini,
  • Mauro Giacca,
  • Marie-Josè Goumans,
  • Lucio Barile,
  • Anke M. Smits,
  • Sveva Bollini

Journal volume & issue
Vol. 25

Abstract

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The data and information presented here refer to the research article entitled: “Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting with the human amniotic fluid stem cell secretome” (Balbi et al., 2019, Apr 04). This dataset illustrates the in vitro paracrine effect exerted by the human amniotic fluid stem cell secretome on rodent neonatal cardiomyocytes, human endothelial progenitors and different subsets of cardiac progenitor cells. Cytokine/chemokine profiling of the human amniotic fluid stem cell secretome is provided as well. This data can provide useful insights in regenerative medicine as demonstrating the in vitro cardioprotective and proliferative secretory paracrine potential of human fetal stem cells. Keywords: Paracrine effect, Human amniotic fluid stem cells, Cardiac progenitor cells, Neonatal cardiomyocytes, Endothelial progenitors, Proliferation, Cardioprotection, Angiogenesis