Nature Communications (Mar 2023)
Turning universal O into rare Bombay type blood
- Itxaso Anso,
- Andreas Naegeli,
- Javier O. Cifuente,
- Ane Orrantia,
- Erica Andersson,
- Olatz Zenarruzabeitia,
- Alicia Moraleda-Montoya,
- Mikel García-Alija,
- Francisco Corzana,
- Rafael A. Del Orbe,
- Francisco Borrego,
- Beatriz Trastoy,
- Jonathan Sjögren,
- Marcelo E. Guerin
Affiliations
- Itxaso Anso
- Structural Glycobiology Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital
- Andreas Naegeli
- Genovis AB
- Javier O. Cifuente
- Structural Glycobiology Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital
- Ane Orrantia
- Immunopathology Group, Biocruces Bizkaia Health Research Institute, Cruces University Hospital
- Erica Andersson
- Genovis AB
- Olatz Zenarruzabeitia
- Immunopathology Group, Biocruces Bizkaia Health Research Institute, Cruces University Hospital
- Alicia Moraleda-Montoya
- Structural Glycobiology Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital
- Mikel García-Alija
- Structural Glycobiology Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital
- Francisco Corzana
- Departamento Química and Centro de Investigación en Síntesis Quı́mica, Universidad de La Rioja
- Rafael A. Del Orbe
- Hematology and Hemotherapy Service, Cruces University Hospital, Biocruces Bizkaia Health Research Institute
- Francisco Borrego
- Immunopathology Group, Biocruces Bizkaia Health Research Institute, Cruces University Hospital
- Beatriz Trastoy
- Structural Glycobiology Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital
- Jonathan Sjögren
- Genovis AB
- Marcelo E. Guerin
- Structural Glycobiology Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital
- DOI
- https://doi.org/10.1038/s41467-023-37324-z
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 16
Abstract
People with the rare Bombay-type Oh blood group can only be transfused with Oh blood. Here, the authors characterize a bacterial α−1,2-fucosidase that can convert universal O type into rare Bombay type blood.
