Purity Assessment of Dinotefuran Using Mass Balance and Quantitative Nuclear Magnetic Resonance
Xianjiang Li,
Wei Zhang,
Xiao Li,
Shukun Zhou,
Mengling Tu,
Yunxiao Zhu,
Hongmei Li
Affiliations
Xianjiang Li
Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China
Wei Zhang
Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China
Xiao Li
Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China
Shukun Zhou
Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China
Mengling Tu
Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China
Yunxiao Zhu
Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China
Hongmei Li
Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China
Dinotefuran (DNT) belongs to the third-generation neonicotinoid pesticides, which are among the most common residuals in a variety of food commodities. To guarantee accurate quantification and traceability of results in food samples, certified reference materials (CRMs) are the indispensable benchmark. In this work, a DNT CRM was characterized and its purity was assessed by two independent methods, including mass balance (MB) and quantitative nuclear magnetic resonance spectroscopy (qNMR). The mass fraction of moisture was 0.33 mg/g, the inorganic impurity was 0.01 mg/g, and no detectable organic solvent was detected. Benzoic acid was chosen as the internal standard for qNMR. Its mass fraction was 997.9 mg/g and 992.9 mg/g by MB and qNMR, respectively. Eventually, the DNT CRM was assigned a mass fraction of 995 mg/g, with expanded uncertainty of 5 mg/g (k = 2). This CRM can be used to prepare calibrant solutions and is applicable to national routine monitoring of DNT residuals in agro-products and food.
