Nature Communications (May 2022)

Proteome allocations change linearly with the specific growth rate of Saccharomyces cerevisiae under glucose limitation

  • Jianye Xia,
  • Benjamin J. Sánchez,
  • Yu Chen,
  • Kate Campbell,
  • Sergo Kasvandik,
  • Jens Nielsen

DOI
https://doi.org/10.1038/s41467-022-30513-2
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

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Understanding how yeast organizes its functional proteome is a fundamental task in systems biology. Here, the authors conduct a multiomics analysis on yeast cells cultured with different growth rates, identifying a linear dependence of the functional proteome on the growth rate.